Oprah is definitely doing her thang with her all star lineups this new season!

On Tuesday, Winfrey will talk to America’s first face-transplant patient. Another guest is “the only living mermaid girl in the world,” as the show bills her. On Wednesday, Mackenzie Phillips (”One Day at a Time”) will talk about a family secret that she kept 31 years. On Thursday, Jay-Z will be on the show and will talk about music and marriage (to Beyonce)- check out the preview below.

Also, Barbra Streisand gives a tour of her new home that day! The Oprah Winfrey Show airs at 4 p.m. weekdays.